Ocular, Neurologic and Systemic Findings of the Cases with Optic Nerve Hypoplasia

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Ocular, Neurologic and Systemic Findings of the Cases with Optic Nerve Hypoplasia

AIM To describe the associated ocular, neurologic, and systemic findings in a population of children with optic nerve hypoplasia (ONH) and to evaluate the relationship between ocular signs and neurologic findings. METHOD A retrospective chart review of 53 patients with the diagnosis of ONH seen between December 1998 and September 2012 was performed. All neurodevelopmental anomalies, neuroradi...

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Hypoplasia of the optic nerve.

Hypoplasia of the optic nerve is uncommon (Scheie and Adler, I94I; Somerville, I962; Whinery and Blodi, I963; Ewald, I967). It is usually due to a failure of development of the ganglion cell layer of the retina and results in a small but discernible optic disc with central vessels. The disc may be cupped with a peripapillary, mottled, yellowish halo corresponding to the size of the normal disc,...

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Optic Nerve Hypoplasia

Congenital anomalies of the optic disc underlie many cases of decreased vision, strabismus, and nystagmus in childhood. A comprehensive evaluation necessitates an understanding of the ophthalmoscopic features, associated neuro-ophthalmologic findings, pathogenesis, and appropriate ancillary studies for each anomaly. The subclassification of different forms of “colobomatous” defects on the basis...

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Spectrum of optic nerve hypoplasia.

Optic nerve hypoplasia is a non-progressive condition characterised by subnormal vision and a subnormal number of optic nerve axons. It may be unilateral or bilateral, isolated or combined with other defects. Analysis of fundus photographs from a series of 7 patients with a stationary abnormality of different degrees showed that the functional defects could be closely correlated with defects in...

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The syndrome of optic nerve hypoplasia.

The congenital malformation known as optic nerve hypoplasia (ONH) has been recognized in the past 30 years as an epidemic cause of congenital blindness. It was believed to occur either as an isolated anomaly or as a component of the syndrome of septo-optic dysplasia, which has evolved to include midline brain malformations and hypopituitarism. Evidence now suggests that ONH infrequently occurs ...

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ژورنال

عنوان ژورنال: The Open Ophthalmology Journal

سال: 2016

ISSN: 1874-3641

DOI: 10.2174/1874364101610010005